Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms.
Population genetic correlates of declining transmission in a human pathogen
Article first published online: 2 NOV 2012
© 2012 Blackwell Publishing Ltd
Volume 22, Issue 2, pages 273–285, January 2013
How to Cite
Nkhoma, S. C., Nair, S., Al-Saai, S., Ashley, E., McGready, R., Phyo, A. P., Nosten, F. and Anderson, T. J. C. (2013), Population genetic correlates of declining transmission in a human pathogen. Molecular Ecology, 22: 273–285. doi: 10.1111/mec.12099
- Issue published online: 3 JAN 2013
- Article first published online: 2 NOV 2012
- Manuscript Accepted: 19 SEP 2012
- Manuscript Revised: 14 SEP 2012
- Manuscript Received: 9 JUL 2012
- Wellcome Trust–Mahidol University–Oxford Tropical Medicine Research Programme
- National Institutes for Health. Grant Number: R37AI048071
- Research Facilities Improvement Program. Grant Number: C06 RR013556
|mec12099-sup-0001-TableS1.txt||plain text document||15K||Tables S1 (GoldenGate SNP assay details) and Table S3 (SNP dataset analyzed) are provided separately as tab delimited text files.|
Table S2 Epidemiology of P. falciparum in children and pregnant women.
Fig. S1 GoldenGate SNP genotyping. Shown here is a typical SNP graph for the A/G SNP on chromosome 14 position 1853537, showing clustering of infections based on their genotypes. Genotype calls are based on the normalized ratio of fluorescence intensity signals for the “A” and the “G” allele in the sample.
Fig. S2 Influence of thresholds used to call MIs. To further determine if the trends observed are robust to the threshold used for categorizing MIs, infections were categorized as MIs using four different threshold values (>1, >5, >10 and >25 heterozygous SNP calls).
Fig. S3 UPGMA tree showing clustering of multilocus genotypes (MLGs) based on the proportion of shared alleles.
Fig. S4 Disparity in malaria in malaria cases among age and sex classes.
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.