Dec 22, 2001
What would be the cause of muscle deterioration in the legs of an HIV positive person resulting in no muscle mass in the legs at all to the point of being wheel chair bound?
Response from Dr. Feinberg
Loss of muscle mass can be seen in severe wasting syndrome, myopathy (disease of muscle itself), or to a brain disorder that interferes with signals that are sent from the brain to the leg muscles, such as PML. There are non-HIV-related diseases that can cause muscle wasting, such as ALS (Lou Gehrig's disease. An individual with sufficient muscle loss to be wheelchair-bound should be evaluated by an HIV specialist and/or a neurologist as soon as possible.
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