IIRC John Hinkley used Devastators in the 22 he used to shoot President Reagan. They were very effective weren't they?
No they did not work, if they had President Reagan may very have died right there but the damage nearly killed him anyway just because of the path the bullet took after it entered his body. If he had used a different gun and the bullets had the right velocity they could have detonated but they didn't.
In fact Hinkley missed with all 6 shots from nearly point blank range hitting windows, secret service guards and secretary Brady instead. The bullet that hit President Reagan was a ricochet off the car.