TechVault PRODUCT DNA/RNA Synthesis Gene Silencing and Small RNAs Genotyping GMP Manufacturing Modifications Molecular Biology Reagents NextGen Sequencing PCR/qPCR Purification QC Information RNase H2 SciTools Applications Synthetic Biology APPLICATION Cloning and Fragment Assembly Gene Silencing and Small RNAs General Oligo Use Genotyping Mutagenesis NextGen Sequencing Oligo Characteristics PCR/qPCR CUSTOMER SUPPORT Account Ordering Pricing and Payment Shipping and Turnaround FAQ/ Tags Can IDT custom synthesize a dual-labeled oligonucleotide (5' FAM/3' TAMRA)? Does my probe sequence need to be modified to convert it to a ZEN double-quenched probe? If ZEN™ is positioned so close to FAM, why is the 3’ quencher required? What is the structure of the ZEN internal quencher? Which dyes are available for use with the IDT ZEN quencher?