Prilosec information from trusted sources:
The active ingredient in PRILOSEC (omeprazole) Delayed-Release Capsules is a substituted benzimidazole, 5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl]-1H-benzimidazole, a compound that inhibits gastric acid secretion. Its empirical formula is C17H19N3O3S, with a molecular weight of 345.42. The structural formula is:Omeprazole is a white to off-white crystalline powder that melts with decomposition at about 155°C. It is a weak base, freely soluble in ethanol and methanol, and slightly soluble in acetone and isopropanol and very slightly soluble in water. The stability of omeprazole is a function of pH, it is rapidly degraded in acid media, but has acceptable stability under alkaline conditions. PRILOSEC is a proton pump inhibitor indicated for: 1.1 Duodenal Ulcer (adults) 1.2 Gastric Ulcer (adults) 1.3 Treatment of Gastroesophageal Reflux Disease (GERD) (adults and pediatric patients) 1.4 Maintenance of Healing of Erosive Esophagitis (adults and pediatric patients) 1.5 Pathological Hypersecretory Conditions (adults) 2 DOSAGE AND ADMINISTRATION 2.1 Short-Term Treatment of Active Duodenal Ulcer 2.2 H. pylori Eradication for the Reduction of the Risk of Duodenal Ulcer Recurrence 2.3 Gastric Ulcer 2.4 Gastroesophageal Reflux Disease (GERD) 2.5 Maintenance of Healing of Erosive Esophagitis 2.6 Pathological Hypersecretory Conditions 2.7 Pediatric Patients 2.8 Alternative Administration Options 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5. WARNINGS AND PRECAUTIONS 5.1 Concomitant Gastric Malignancy 5.2 Atrophic Gastritis 5.3 Combiniation Use of PRILOSEC with Amoxicillin 5.4 Combination Use of PRILOSEC with Clarithromycin 6 ADVERSE REACTIONS 6.1 Clinical Trials Experience with PRILOSEC Monotherapy 6.2 Clinical Trials Experience with PRILOSEC in Combination Therapy for H. pylori Eradication 6.3 Post-marketing Experience 7 DRUG INTERACTIONS 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.3 Nursing Mothers 8.4 Pediatric Use 8.5 Geriatric Use 8.6...
The active ingredient in PRILOSEC (omeprazole) Delayed-Release Capsules is a substituted benzimidazole, 5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl]-1Hbenzimidazole, a compound that inhibits gastric acid secretion.
Omeprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers and gastroesophageal reflux disease (GERD), a condition in which the acid in the stomach washes back up into the esophagus. Sometimes omeprazole is used in combination with antibiotics to treat ulcers associated with infection caused by the H. pylori bacteria (germ).
Prilosec is prescribed for the short-term treatment (4 to 8 weeks) of the following:
National Committee for Clinical Laboratory Standards. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. Fifth Edition: Approved Standard NCCLS Document M7-A5, Vol. 20, no. 2, NCCLS, Wayne, PA, January 2000.