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|United States Patent||7,052,691|
|Sleeman , et al.||May 30, 2006|
Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as a VEGF trap capable of binding and blocking VEGF.
|Inventors:||Sleeman; Mark W. (Mahopac, NY), Wiegand; Stanley J. (Croton-on-Hudson, NY)|
Regeneron Pharmaceuticals, Inc.
|Filed:||March 26, 2004|
|Application Number||Filing Date||Patent Number||Issue Date|
|Current U.S. Class:||424/134.1 ; 424/192.1; 514/21.2; 514/8.1; 530/350; 530/387.3; 536/23.4|
|Current International Class:||A61K 38/18 (20060101); C07K 14/71 (20060101); C12N 15/62 (20060101)|
|6524583||February 2003||Thorpe et al.|
|2003/0017977||January 2003||Xia et al.|
|WO 02/060489||Aug., 2000||WO|
|WO 00/75319||Dec., 2000||WO|
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