It is unlikely that having 1 drink would cause swelling of the hands and feet. In rare cases, drinks that have high concentrations of histamine (such as certain wines) may cause a histamine-like reaction in certain sensitive people, but this usually manifests as gastrointestinal discomfort or worsening of asthma
symptoms. Another more likely possibility is that your friend has a variant in one of the enzymes that breaks down alcohol; this is quite common and can lead to blushing or flushing or blotchiness of the skin, but is not a true allergic reaction.
True allergic reaction to alcohol (ethanol) is technically possible but would be very, very rare. However, if your friend has any of the following concerning symptoms when drinking alcohol, she should immediately seek medical attention: swelling of the face, lips or tongue; wheezing or difficulty breathing; violent nausea, vomiting
, and abdominal pain.
In people with an underlying medical problem, such as a liver or heart problem, drinking alcohol can lead to problems with how the body handles fluid and this can definitely lead to swelling. Therefore, if your friend has any serious medical problems, this is a possibility.
The best advice would be for her to see her primary care doctor