Purpose. To evaluate the current status of materials in use for corneal refractive therapies.
Methods. The most up-to-date data available on rigid gas-permeable (RGP) lenses, corneal swelling, and corneal infection are reviewed.
Results. Despite 125 Dk/t units or greater, studies have shown differences in overnight swelling between RGP and silicone hydrogel materials. There is a small but significant overnight swelling with RGP lenses in this class when compared with silicone hydrogels, yet studies of Pseudomonas adherence to human epithelium have shown that RGP-wearing corneas bind the least bacteria.
Conclusions. Corneal refractive therapies are on the verge of international acceptance as a standard alternative for treating refraction. Continually using newer, more permeable lens materials is a necessity to ensure safety, efficacy, and, in turn, long-term acceptance.