A question of probability.
toby at stein1.u.washington.edu
Thu Oct 14 16:36:49 EST 1993
In article <1993Oct14.144422.1 at kean.ucs.mun.ca>,
<roger at kean.ucs.mun.ca> wrote:
> When searching for linkage to a previously unknown locus, a LOD of
>3.0 approximates to a 95% probability of linkage (not the 1000 to 1
>odds frequently cited).
That depends on the map length and marker density, hence the number
of "independent" tests.
>How is this changed if we are looking for linkage to
>a single candidate locus as in the present example?
In a single test, the LOD score and p value are the same, if my
intuition is correct. Ellen Wijsman -- are you listening?
Toby Bradshaw |
Department of Biochemistry | Will make genetic linkage maps
and College of Forest Resources | for food.
University of Washington, Seattle |
toby at u.washington.edu |
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