bBBr is one of the most popular thiol-reactive fluorescent tags, and is widely used to detect various thiol-containing biomolecules such as glutathione in cells. It is fluorogenic upon reacting with thiol-containing molecules.
Loo TW and Clarke DM (2000). Identification of residues within the drug-binding domain of the human multidrug resistance P-glycoprotein by cysteine-scanning mutagenesis and reaction with dibromobimane. J Biol Chem 275, 39272-8; Bonet A, et al. (1988). The internal crosslinking of the S1 heavy chain from smooth muscle probed by dibromobimane. Biochem Biophys Res Commun 152, 1-8.