GEM4’s objective is to educate researchers and graduate students about the fundamentals of cell and molecular biomechanics, and to provide an intense learning experience, and to facilitate interactions among engineers, biologists and clinicians. The goals are to help train a new generation of researchers with in-depth knowledge of mechanics and biology and to help engineers and biologists apply biomechanical approaches in biomolecular, cellular, tissue-level, animal model studies.
Dennis' research efforts in the nano/bio realm range from stem cell-matrix interactions and high-accuracy proteomics to polymer-based nano-delivery of drugs. His lab pioneered studies of stem cell differentiation due to matrix elasticity and Mass Spectrometry approaches to folding at the proteomic scale. His lab has also developed novel degradable cylinders known as filomicelles as well as degradable polymersomes that shrink tumors and treat genetic diseases.
MIT, NSF, GEM4, MechSE
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Massachusetts Institute of Technology, Cambridge, MA