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Zuska's disease (also known as lactiferous fistula, subareolar abscess, periductal mastitis, and Zuska–Atkins disease) is a rare recurrent condition characterized by draining abscesses around the nipple. Smoking is a predisposing factor. It can mimic carcinoma of breast and is often misdiagnosed and mistreated, occasionally resulting in unnecessary mastectomy. Symptoms include swelling or subareolar mass, a draining fistula from behind the areola, nipple retraction, thick discharge from the nipple, or painful discharge. It is treated by antibiotics and surgical excision of breast.
The definitive therapy involved excision of the fistula and all of the retroareolar fibroglandular tissue, along with ductal tissue within the nipple.
It was characterized by Joseph Zuska in 1951.
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