Revista chilena de radiología
versión On-line ISSN 0717-9308
VALENZUELA P, Raúl y CATALAN V, TM. Humberto. SCREENING OSEO PANESQUELETICO: ESTUDIO DE MEDULA OSEA CON RM USANDO SECUENCIAS T1 (SORM). Rev. chil. radiol. [online]. 2004, vol.10, n.1, pp. 16-21. ISSN 0717-9308. http://dx.doi.org/10.4067/S0717-93082004000100005.
Abstract. Objective: Bone Marrow MRI Screening (BMMS) using large FOV T1 sequences span a wide spectrum of abnormalities from stress bone fractures to malignant metastatic lesions. The purpose of this study was to evaluate the use of BMMS in the assessment of bone marrow abnormalities in a group of patients with high metastatic or metabolic risk. Materials and methods: The study displays a selection of 34 cases selected and gathered by the authors in the 2000-2003 period, using a 1.0 Tesla unit Siemens Magnetom Impact. The study protocol includes five T1-weighted sequences FOV 500 TR 400 TE 10 5mm 3NEX applied in 3 body segments: coronal and sagittal of skull and chest segment, coronal and sagittal in the lumbar, pelvic and proximal lower limbs segment and only coronal in the lower limbs segment. Results were compared with Nuclear Medicine Bone Scans (BS), using as Gold Standard the final Clinical Diagnostic Summary of the Hospital Cancer Board in wich diverse evidence were considered including hystologic analysis of biopsy samples. Results: The gender proportion in the studied group was of 53% female and 47% male subjects. 71% were older than 60 years old and 79% were at high risk of metastatic bone disease. BMMS showed in the high metastatic risk group an incidence of 48% of bone metastatic disease and an incidence of 41% of bone stress fractures. The degree of agreement between BMMS and the Gold Standard was of a 100%, and the overall disagreement rate between BMMS and BS was 37% in the metastatic risk group. Conclusion: This study shows that BS results provides information that leads to an inaccurate tumoral staging in 26% of cases in the high metastatic risk group, inducing in most cases to further imaging studies as MRI, CT or X-ray films. BMMS shows its usefulness being not only specific and sensitive but also cost effective as a single study in the assessment of bone disease in elder patients at high metastatic risk
Palabras clave : Bone Marrow MRI; Bone strees fracture; Metastatic bone disease.