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|De novo malignancies following liver transplantation: impact and recommendations|
|Authors: ||Herrero, J.I. (José Ignacio)|
|Keywords: ||Liver transplantation/adverse effects|
|Issue Date: ||2009|
|Publisher version: ||http://onlinelibrary.wiley.com/doi/10.1002/lt.21898/pdf|
|Citation: ||Herrero JI. De novo malignancies following liver transplantation: impact and recommendations. Liver Transpl 2009 Nov;15 Suppl 2:S90-4.|
1. De novo malignancy is one of the leading causes of
late mortality after liver transplantation.
2. The risks of skin cancers and lymphoma are more
than 10-fold greater than the risks in an age-matched
and sex-matched general population.
3. Some types of neoplasia, such as lung, head and
neck, and colorectal cancer, are more frequent in liver
transplant recipients than in an age-matched and sexmatched
population. The risks of other frequent malignancies,
such as prostate and breast cancer, do not
seem to be increased.
4. The most important risks for posttransplant malignancy
are Epstein-Barr virus seronegativity (for lymphoma),
sun exposure (for skin cancer), smoking, and
5. Despite the absence of evidence, general recommendations
(such as avoidance of overimmunosuppression,
sunlight protection, and cessation of smoking)
should be given. Screening protocols may help to
detect neoplasia at an early stage of disease.
|Permanent link: ||http://hdl.handle.net/10171/22544|
|Appears in Collections:||DA - CUN - Hepatología - Artículos de revista|
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||Liver Transpl 2009. s90.pdf|
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