Claude Chelala achieved a Ph.D. degree in radiation biology from the University of Paris-Sud and an academic degree in structural bioinformatics from Paris Descartes University. Chelala's worked at the CNRS on the development of tools to gather information for automated analysis of genome maps and distribution study of the disease-related genes. Afterwards, Chelala joined the Pasteur Institute to work on large-scale analysis of genetic variation, integration with clinical data, and the association with type 1 diabetes. Chelala worked on developing tools to transfer, integrate, and analyse the genetic, genomic, and proteomic data. Funded by Cancer Research UK, Chelala joined Barts Cancer Institute as a Senior Lecturer and Principal Investigator in bioinformatics. An important aspect of her work involves designing and setting up a generic model for the organisation, integration and mining of complex omics datasets. This model was successfully applied to pancreatic and breast cancer. She is also interested in the study of genetic variations and has designed and implemented SNPnexus as a dedicated resource which allows scientists to functionally annotate newly discovered or public domain SNPs. In addition, her computational work covers large-scale analysis of common/specific alteration signatures in human cancers in order to identify cancer-causing genes, cancer-related molecular pathways, and new biomarkers for novel diagnostics or screening in cancer.
Biography Updated on 10 March 2013