Engines of this number of cylinders are not common in automobiles, but this configuration is used in some large diesel engines.
For example, the 1960s vintage EMD SD45 diesel-electric locomotive is fitted with a 20-cylinder EMD 645E3 two-stroke engine. The engine name is based on the displacement of each cylinder in cubic inches. In this case, it is 645 cubic inches (10.6 L) for each of 20 cylinders for a total of 211 L. Power output is 3,600 horsepower (2.7 MW).
EMD later produced a 20-cylinder 710 series diesel engine for the EMD SD80MAC locomotive. EMD still manufactures these engines, which are primarily used in the power production and marine industries. An EMD 20-710 can produce over 5,000 horsepower.
V20 diesel engines have also been used in marine applications: Mercedes-Benz has produced one such engine. Wärtsilä also currently produces a V20 engine for use in power plants that can produce 13,500 horsepower (10 MW).