Researchers Develop Editing Toolkit for Zebrafish Genome
Mayo Clinic researchers and an international team of scientists have developed a highly-efficient means of editing zebrafish genomes for research purposes, eliminating a bottleneck that has stymied biomedical scientists from using the fish as a model for human disease. The details appear online in the journal Nature.
For many researchers, zebrafish are becoming the model of choice for genetic studies. However, the inability to efficiently target genetic modifications has delayed their use by some. The Mayo team used an improved variant of artificial transcription activator-like effector nucleases, or TALENs, to provide a new approach.
Read more: http://www.laboratoryequipment.com/news/2012/09/researchers-develop-editing-toolkit-zebrafish-genome