Data Presented at the American Academy of Neurology Show XP13512/GSK1838262 Significantly Improved Symptoms of Moderate-to-Severe Primary Restless Legs Syndrome
... on the CGI-I Scale compared to placebo
(38.9 percent; P<0.0001).
is often associated with RLS. In this clinical trial,
patients completed ... sleep adequacy, as well as
statistically significant reductions in sleep disturbance
The PIVOT RLS I clinical trial used a 24-hour ...
Cethromycin Achieves All Endpoints in Second Pivotal Phase III Trial for Treatment of Pneumonia
... Biaxin 1.0%), abdominal
pain (cethromycin 1.4%, Biaxin 1.4%) and taste disturbance
7.6%, Biaxin 2.1%). No drug-related serious adverse events ... (4/288) (4/291) (4/260) (8/257) (8/548) (12/548) Taste disturbance
7.6% 2.1% 11.2% 6.2% 9.3% 4.0% ...
Post-Hoc Data Show Daily Activity Participation, Independence and Sleep Quality Improved in Adults with Moderate to Severe Rheumatoid Arthritis After Treatment with ORENCIA(R) (Abatacept)
... ORENCIA group and 0.6 in the
placebo group (p-value equals 0.0028), sleep disturbance
was -11.3 in the
ORENCIA group and -2.9 in the placebo group (p-value ... different in the ATTAIN group.
In the AIM study, measurement of sleep disturbance
in the ORENCIA group was
-13.0 and -8.9 in the placebo group (p-value ...
Risks of Delaying ACL Reconstruction in Young Athletes May Be Too High, Study Shows
... benefits and risks of repairing a torn anterior cruciate ligament (ACL) in young athletes under the age of 14.
"The risk of inducing a growth disturbance
with early reconstruction of a torn ACL must be balanced against the risk of further knee damage by delaying treatment until closer to skeletal ...
BioCis Pharma Reports Positive Phase IIa Clinical Results in Atopic Dermatitis
... BioCis Pharma. "Skin barrier dysfunction is now
recognized as a hallmark feature of atopic dermatitis. Any drug showing
capacity for restoring this disturbance
has significant potential in atopic
dermatitis therapy. Based on our results, ProtoCure(TM) emulsion cream holds
great promises in the treatment of ...
Major Restless Legs Study Completes Enrollment With Support From MediciGlobal
... are inherited. A serious and common side effect is sleep disturbance.
The recruitment campaign encouraged those diagnosed with RLS and sleep disturbance
to seek out the clinical study. An education based approach reached undiagnosed RLS sufferers. Furthermore, MediciGlobal engaged study sites and the ...
Retigabine Significantly Reduces the Number of Seizures in Adults With Inadequately Controlled Partial-Onset Epilepsy
... About Epilepsy
Epilepsy, defined by recurrent, unprovoked seizures, is a change in
sensation, awareness or behavior caused by an electrical disturbance
brain. The kind of seizure a person has depends on which part and how much of
the brain is affected by the disturbance. Primary generalized ...
New Data Shows Prescription Omega-3 Acid Ethyl Esters Reduced the Incidence of Death in Heart Failure Patients
... rate of treatment
discontinuation due to adverse reactions was the same in both groups. The
most commonly reported adverse event was gastrointestinal disturbance
the rate of occurrence (3%) was similar in both groups.
LOVAZA is made from nature, and is the first and only U.S. Food and
European CHMP Issues Positive Opinion on Cymbalta for the Treatment of Generalised Anxiety Disorder
... and poor concentration. Ability to work is
often compromised with the manifestation of physical symptoms such as
muscle tension, fatigue, sleep disturbance
and nausea.(12) The illness
tends to be chronic with periods of exacerbation and remission. Patients
report that episodes of generalized anxiety ...
Eribulin Mesylate Demonstrated Anti-Tumor Activity in Heavily Pretreated Patients with Advanced Breast Cancer
... 5.5%, leukopenia (low white blood cell count, 14%), and
weakness/fatigue (10%; no Grade 4 events). Grade 3 peripheral neuropathy (a
or damage to nerves outside the brain and spinal
cord) was reported in 5.5% of patients. No Grade 4 peripheral neuropathy
events were reported. No ...
Circulation Publishes Data Showing KYNAPID(TM) (Vernakalant Hydrochloride) Injection Rapidly Converted Short-Duration Atrial Fibrillation to Sinus Rhythm
... dosing in the short-duration AF group.
The most common adverse events (AEs) reported within the first 24 hours
in patients given KYNAPID were taste disturbance
(29.9%), sneezing (16.3%),
skin sensation (10.9%), nausea (9%), and hypotension (6.3%). These events
were generally transient. Four serious AEs ...
Medivation's Dimebon(TM) Stabilizes Behavioral Symptoms in Alzheimer's Disease Patients, Resulting in Reduced Caregiver Distress
... were seen across most behavioral symptoms and were most prominent
in the symptoms of depression, apathy, hallucinations, irritability and
(i.e., engaging in repetitive activities, such as pacing
around the house). The data were presented today during a poster session on
new research ...
New Clinical Data Further Supports Chromium Picolinate's Role in Enhancing Brain Activity in Older Adults
... < .0001). There was no
significant difference between the groups with respect to age (72 versus 73
years), education (15.8 versus 17.3 years), mood disturbance
(11 versus 4.5
Profile of Mood States score), and level of memory impairment (.89 versus
.63 Clinical Dementia Rating sum boxes score).
Alexza's AZ-104 (Staccato(R) Loxapine) Phase 2a Trial Meets Primary Endpoint of 2-Hour Pain Relief in Patients with Migraine Headache
... 5 2 5 5 Hypoaesthesia, oral 0 2 5 2 Attention disturbance
0 5 0 2 Hypotension 3 0 2 5
About Acute ...
New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy
... electrical disturbances
in the brain. The kind of seizure a person has depends on which part and
how much of the brain is affected by the electrical disturbance
produces seizures. Generalized seizures are seizures that involve the
entire brain from the outset. Partial seizures, which are the most ...
Analysis Shows Vernakalant Hydrochloride Injection Increases Conversion to Normal Heart Rhythm in Acute Atrial Fibrillation Patients Treated Within 48 Hours of Onset
... percent of vernakalant responders required only one dose of
the drug. The most common adverse events (AEs) in patients given vernakalant were
(32.4 percent), sneezing (16.7 percent), nausea (15.7
percent) and dizziness (11.8 percent). The incidence of serious AEs was
similar in the ...
CardioFocus Endoscopic Ablation System Earns CE Mark to Treat Atrial Fibrillation; US Clinical Investigation Underway
... vein isolation
for the treatment of atrial fibrillation. The Endoscopic Ablation System has been designed to treat the most
common heart rhythm disturbance
called atrial fibrillation, a disease
affecting more than 5 million people in Europe and in the United States in
addition to millions more worldwide. ...
Addex Achieves Statistically Significant Outcome in Phase IIa
Clinical Trial With ADX10059 in Gastro-Esophageal Reflux Disease
... period (p = 0.013). Importantly, night time
reflux, which is often poorly controlled by conventional
acid-suppressing therapies and results in sleep disturbance
increased risk of esophageal damage, was also significantly reduced
by ADX10059 (p = 0.0021).,
The benefits on the physiological measures of ...
Ceragenix Announces Results from Phase IV Study of EpiCeram Meet
All Primary and Secondary Endpoints
... at Day 28;
b) Change in patient reported assessments of pruritus (itch);
c) Change in patient reported assessment of disturbance
Primary Outcome Measure (change in mean SCORAD score measured at
Day 28 compared to Baseline).
New Data Shows Once a Day Lamictal XR is Effective in Treating
Patients with Partial Seizures
disturbance in the brain. The kind of seizure a person has depends
on which part and how much of the brain is affected by the
that produces seizures. Generalized seizures
are seizures that involve the entire brain from the outset. Partial
seizures, which are more common, ...
Data Suggest Cymbalta Improved Functioning in Patients with
Generalized Anxiety Disorder
... each year.(4) Symptoms persist for at
least six months and can include exaggerated worry or chronic
anxiety, irritability, poor concentration, sleep disturbance
fatigue.(5,6) Generalized anxiety disorder may be brought on, or
worsened by, stressful life events. The illness also tends to be
chronic with ...
New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk
... Meanwhile, a skin sterol test called PREVU(x) provides a convenient, non-invasive, Point-of-Care assay.
At the root of atherosclerosis is a disturbance
of the inner (intimal) wall of the artery. The process is complex, but one component is usually hypertension, which contributes to turbulent blood ...