Can metformin, Actos, or glipizide ER cause bloating?
- Q: My husband has type 2 diabetes and is on metformin, Actos and glipizide ER. He always seems to feel and look bloated. Can any of these medicines be the cause of bloating?
- A: Metformin is a medication that is used to treat type 2 diabetes. Metformin is in the group of medications called biguanides that work by decreasing the amount of glucose absorbed through the diet, decreases production of glucose in the liver, and makes insulin receptors more sensitive so the body can utilize its own insulin more efficiently. The prescribing information on metformin lists the following as common side effects of the medication: diarrhea, gas, nausea, indigestion, stomach discomfort, and headache. Actos (piogltazone) is a medication that is used to treat type 2 diabetes. It is in a group of medications called glitazones that work by improving insulin sensitivity which allows the body to utilize insulin more effectively. The prescribing information on Actos lists the following as common side effects of the medication: headache, sinus infection, muscle pain, tooth problems, sore throat, and swelling or fluid retention. Glipizide ER or XL is a medication that is used to treat type 2 diabetes. It is in the group of medications called sulfonylureas that work by helping the pancreas produce more insulin and making the cells respond better to the insulin. The prescribing information on glipizide ER lists the following as common side effects of the medication: dizziness, diarrhea, gas, nervousness, and shakiness. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmD
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