These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Crowning Moment of Funny: Lizzie has to give out balloon animals at the halloween dance in Night of the Day of the Dead, but she doesn't know how to make any. So she gives out a bunch of narrow balloons saying, "Here, it's a snake" or "Here it's a worm". After giving her brother, Matt, a "caterpillar", he tells her, "This is a lame balloon animal" to which she replies, "Oh, sorry. Let me fix it." She then pops the balloon and says "Ooh, there. Now it's extinct."
Epileptic Trees: There is a theory that is circulating around the Internet that Lizzie is a schizophrenic. It also partially explains why the show starts in middle school, and why Lizzie's friend Miranda disappeared from the show (even though the show states that she went to Mexico with her family). The theory can be read here .