Autonomic Nervous System, Fatigue and Intolerance to Physical Training, and Overtraining in High-Level Athletes
Sports training aims to enhance an athlete's performance (overcompensation). To do that, the athlete must go through periods of fatigue and lower performance (overreaching). When the training plan is balanced, this fatigue is short and reversible.If the training load is too heavy or if recuperation periods are too short, it can lead to persistence fatigue that may only be reversible in the long term. This state of fatigue is part of the broader clinical picture of overtraining, which includes stark changes in performance as well as mood and sleep disorders. Many prediction and characterization methods based on biological markers have been evaluated, but they have not been put into practice in sports training due to obstacles such as reliability, interindividual variability and high costs. This study aims to evaluate a new approach based on the variability of an individual's heart rate (RR variability), which is a way of measuring autonomic nervous system (ASN) activity. It is non-invasive, low-cost, and has already proven useful in athlete health monitoring.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Autonomic Nervous System, Fatigue and Intolerance to Physical Training, and Overtraining in High-Level Athletes. A Multicentre Study|
- Autonomic nervous system (ANS) activity [ Time Frame: One year ] [ Designated as safety issue: No ]This ANS is mesured during the night using a spectral analysis of nocturnal heart rate variability.
- Fatigue and physical training [ Time Frame: One year ] [ Designated as safety issue: No ]Fatigue and physical training potetially due to overtraining, suspected based on a very significant, long-term worsening in performance
- kinetic of the ANS activity [ Time Frame: Every 15 days (from the iclusion to one year) ] [ Designated as safety issue: No ]ANS is mesured during the night using a spectral analysis of nocturnal heart rate variability
- orthostasis test [ Time Frame: Every 15 days (from inclusion to one year) ] [ Designated as safety issue: No ]ANS activity measurements (RR variability) during active orthostasis transition on waking up in the morning
- French Society of Sports Medicine questionnaire [ Time Frame: Every 15 days (from inclusion to one year) ] [ Designated as safety issue: No ]The questionnaire was designed to detect early signs of overtraining. It includes 54 yes/no questions. Subjects who answer "yes" to more than 20 questions are considered at risk for overtraining.
- POMS (Profile of Mood States) questionnaire [ Time Frame: Every 3 months (from inclusion to inclusion) ] [ Designated as safety issue: No ]
- Sleep quality questionnaire [ Time Frame: Every 3 months (from inclusion to one year) ] [ Designated as safety issue: No ]The questionnaire is self-administered. It includes two parts. The first part consists of several questions regarding sleep during the previous night. The second part aims to evaluate the physical exertion load during the previous day's training session(s). Participants will fill one questionnaire/day for a whole week. Each questionnaire period must coincide with a training period (interseason, volume, intensity, or competition.)
|Study Start Date:||July 2010|
|Study Completion Date:||December 2012|
|Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
High-level athlete, enrolled in a Ministry-recognized Pôle
Device: ANS activity
This ANS activity is measured by nocturnal heart rates records with Holter ECG.
The investigators propose to describe the variation of these ANS regulation factors over a full year, in a population of high-level athletes, in order to measure changes in regulation which may be predictive of potential fatigue and intolerance to physical training, if such a syndrome came to be observed among the study group.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01463761
|CH Albertville Moutiers|
|Albertville, France, 73200|
|CHU de Besançon|
|Besancon, France, 25000|
|Université Paris XIII|
|Bobigny, France, 93000|
|CHU de Grenoble|
|Grenoble, France, 38000|
|CHU de Pointe à Pitre|
|Pointe A Pitre, France, 97110|
|CNSN Centre médical de Prémanon|
|Premanon, France, 39400|
|CHU de Saint-Etienne|
|Saint-Etienne, France, 42000|
|CREPS Toulouse Midi Pyrénées|
|Toulouse, France, 31000|
|Principal Investigator:||Frederic ROCHE, MD PhD||CHU de Saint-Etienne|
|Study Chair:||Xavier BIGARD, MD PhD||Institut de Recherche Biomédicales des Armées|