dergulated, inspires cells to multiply beyond their normal sphere, with deleterious effects on their host.
Leder's research involved the implantation of mice with what he hypothesized was the dangerous form of the gene. When the offspring of the experimental group developed cancer, Leder concluded that he had correctly pegged the villainous agent.
"We have developed a system which could be used to define the other genes that are involved in malignancy," Leder said About 20 oncogenes have already been discovered.
Leder is the Harvard Medical School professor to receive the an annual award, now in its eighth year.
The two researchers will formally accept their prizes at a luncheon at New York's Waldorf-Astoria Hotel on April 11.
Leder will present a lecture on "Misplaced Genes" that will touch on his research as part of the Research Lectures for Non-Specialists series in Science Center B beginning at 8 p.m. tonight.