The Sanford Project
The mission of The Sanford Project is to identify and deliver a cure for type 1 diabetes in Denny Sanford’s life time.
The Sanford Project is an emerging translational research center focused on targeted diabetes research, cures and care.
Worldwide, about 70,000 children aged under 14 years are developing type 1 diabetes per year. Type 1 diabetes, also termed juvenile-onset or insulin-dependent diabetes, is an autoimmune disease and metabolic disorder characterized by an immune-mediated destruction of insulin-secreting beta-cells of the pancreas, resulting in insulin deficiency and hyperglycemia. The primary clinical signs of type 1 diabetes are ketoacidosis - which can lead to coma and death - and chronic hyperglycemia. Chronic hyperglycemia is the primary cause of several macrovascular and microvascular diabetic complications. Insulin-replacement therapy is the life-saving first-line treatment for people diagnosed with type 1 diabetes. Insulin-replacement therapy is, however, not a cure and cannot prevent the further progression of the disease and the development of long-term diabetic complications. Thus, the identification of disease-modifying therapies and cures remain a major unmet medical need and the focus of The Sanford Project.
The Sanford Project team:
To succeed a unique partnership has been put in place between The Sanford Project team, Sanford Clinical Research, and the Sanford family of Hospitals & Clinics. It is complemented in its activities by the national and international network of Sanford Children's Clinics and the Sanford-Burnham Medical Research Institute with operations in La Jolla, CA and Orlando, FL.
The Sanford Project Faculty: