A library with specialist information for people with disabilities, at the Strathmont Centre at Oakden in Adelaide, is expected to close by the end of October.
The South Australian Government said it wanted to move the resources to a community-based library.
The entire Strathmont Centre, for people with physical and intellectual disabilities, will close by the end of next year.
Its residents are being moved to community housing.
Dignity for Disability MLC Kelly Vincent urged the Government to find a suitable location for the library resources.
"Details of where it would be located to are important because obviously, for example, if it's a disability resource library relocating to an inaccessible venue that's going to be problematic," she said.