In univariate analyses, baseline temperature significantly correlated with the average number of TPs at the initial (r = 0.21, P = .007), 2-month (r = 0.30, P<.001), and 6-month (r = 0.20, P = .02) visits. Other baseline variables associated with more TPs at 2 months included lower viral capsid antigen IgG (r = −0.20, P = .01), worse social functioning (r = −0.16, P = .049), and less social support from family (r = −0.16, P = .049). A higher TP count at 6 months was related to poorer health (r = −0.17, P = .047). Thus, baseline variables used in the regression included the SF-36 social and general health subscales, the family social support measure, temperature, and viral capsid antigen IgG titers. After controlling for age and sex, the multiple regression analyses were significant for TPs at baseline (F3,145 = 6.70, P<.001, R2 = 0.12), 2 months (F4,137 = 23.12, P<.001, R2 = 0.40), and 6 months (F4,136 = 11.27, P<.001, R2 = 0.25). The only variable associated with TPs at presentation was initial temperature (t = 3.57, P<.001), with higher temperatures being associated with more TPs. After also controlling for baseline TPs, social support from family at illness onset predicted TPs at both 2 (t = −2.73, P = .007) and 6 months (t = −2.36, P = .02), with less support associated with more TPs. Female sex was associated with more TPs at 2 (t = 2.93, P = .004) and 6 months (t = 2.17, P = .03), as was age (t = 3.54, P<.001, and t = 2.88, P<.005). Finally, baseline TP count was significant in the 2-month (t = 7.61, P<.001) and 6-month (t = 5.13, P<.001) models.