Cortical thinning in cingulate and occipital cortices in first episode schizophrenia.
|Title||Cortical thinning in cingulate and occipital cortices in first episode schizophrenia.|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Narr, KL, Toga AW, Szeszko P, Thompson PM, Woods RP, Robinson D, Sevy S, Wang YP, Schrock K, Bilder RM|
|Date Published||2005 Jul 1|
|Keywords||Adult, Age Factors, Antipsychotic Agents, Brain Mapping, cerebral cortex, Female, Gyrus Cinguli, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Male, Occipital Lobe, Schizophrenia, Sex Factors|
Postmortem studies examining discrete regions show reduced cortical thickness in schizophrenia. Computational image analysis methods allow spatially detailed cortical thickness measurements across the entire cortex in 3D, but have not addressed thickness changes in cingulate or other cortices bordering the medial walls of the cerebral hemispheres in first episode schizophrenia.
|Alternate Journal||Biol. Psychiatry|