Short and prolonged acute CBF drops during SAH. (A) Representative laser-Doppler CBF measurements obtained during the first 30 min after induction of SAH. Curves are typical examples of the course of a short acute CBF drop (black curve) and a prolonged acute CBF drop (red curve). (B) Same representative laser-Doppler measurements as in (A), but depicted as the reduction in CBF as % of baseline values. Shown are typical examples of area under the curve (CBF-AUC) for a short acute CBF drop (grey area) and a prolonged acute CBF drop (red area). (C) Bar graph showing mean CBF-AUC values for the first 2 minutes after SAH (CBF-AUC2 min) and the first 20 minutes after SAH (CBF-AUC20 min) for SAH rats with short and prolonged acute CBF drops, respectively. Error bars are all s.e.m. **: p < 0.01 as determined by student’s t-test.
Povlsen et al. BMC Neuroscience 2013 14:34 doi:10.1186/1471-2202-14-34