Screening the yeast genome for new DNA-repair genes
Wellcome/Cancer Research UK Institute of Cancer and Developmental Biology and Department of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
Genome Biology 2002, 3:reviews1009-reviews1009.5 doi:10.1186/gb-2002-3-4-reviews1009Published: 13 March 2002
Studies of DNA repair and the maintenance of genomic integrity are essential to understanding the etiology and pathology of cancer. The availability of the complete genome sequence of Saccharomyces cerevissiae has greatly facilitated the discovery of new genes important for DNA repair.