User: Can you estimate if the molecule with the SMILES COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C is permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: Yes, this molecule is permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, this molecule is {p_np#not &NULL}{p_np__names__adjective}.
COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C
COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C
(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one