User: Is the molecule with the SMILES O=C(Cc1ccc(Cl)c(Cl)c1)N1CCN(CCO)C[C@@H]1CN1CC[C@@H](O)C1 permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: No, it is not permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Is the molecule with the {SMILES__description} {SMILES#} {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, it is {p_np#not &NULL}{p_np__names__adjective}.
O=C(Cc1ccc(Cl)c(Cl)c1)N1CCN(CCO)C[C@@H]1CN1CC[C@@H](O)C1
O=C(Cc1ccc(Cl)c(Cl)c1)N1CCN(CCO)C[C@@H]1CN1CC[C@@H](O)C1
2-(3,4-dichlorophenyl)-1-[(2R)-4-(2-hydroxyethyl)-2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]piperazin-1-yl]ethanone