User: Is the molecule with the SMILES COC1CCCC2C1=C(C(=O)[O-])N1C(=O)C(C(C)O)C21 permeable through the blood-brain barrier?
Assistant: No, it is not permeable through the blood-brain barrier.
User: Is the molecule with the {SMILES__description} {SMILES#} {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, it is {p_np#not &NULL}{p_np__names__adjective}.
COC1CCCC2C1=C(C(=O)[O-])N1C(=O)C(C(C)O)C21
COC1CCCC2C1=C(C(=O)[O-])N1C(=O)C(C(C)O)C21
1-(1-hydroxyethyl)-5-methoxy-2-oxo-5,6,7,8,8a,8b-hexahydro-1H-azeto[1,2-b]isoindole-4-carboxylate