User: Can you derive if the molecule with the SMILES COC(OC)C(=O)[C@@]12OC(C)(C)O[C@@H]1CC1C3C[C@H](F)C4=CC(=O)C=CC4(C)[C@@]3(F)C(O)CC12C is permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: Yes, this molecule is permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, this molecule is {p_np#not &NULL}{p_np__names__adjective}.
COC(OC)C(=O)[C@@]12OC(C)(C)O[C@@H]1CC1C3C[C@H](F)C4=CC(=O)C=CC4(C)[C@@]3(F)C(O)CC12C
COC(OC)C(=O)[C@@]12OC(C)(C)O[C@@H]1CC1C3C[C@H](F)C4=CC(=O)C=CC4(C)[C@@]3(F)C(O)CC12C
(4R,8S,12R,19S)-8-(2,2-dimethoxyacetyl)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one