User: Is the molecule with the SMILES COC(=O)C1C2CC3c4[nH]c5cc(OC)ccc5c4CCN3CC2CC(OC)C1OC permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: Yes, it is permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Is the molecule with the {SMILES__description} {SMILES#} {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, it is {p_np#not &NULL}{p_np__names__adjective}.
COC(=O)C1C2CC3c4[nH]c5cc(OC)ccc5c4CCN3CC2CC(OC)C1OC
COC(=O)C1C2CC3c4[nH]c5cc(OC)ccc5c4CCN3CC2CC(OC)C1OC
methyl 6,17,18-trimethoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate