User: Is the molecule with the SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC permeable through the blood-brain barrier?
Assistant: No, it is not permeable through the blood-brain barrier.
User: Is the molecule with the {SMILES__description} {SMILES#} {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, it is {p_np#not &NULL}{p_np__names__adjective}.
COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline