User: Is the molecule with the SMILES CC(=O)N1CCN(C(=O)Cc2ccc(C(F)(F)F)cc2)[C@@H](CN2CC[C@@H](O)C2)C1 permeable through the blood-brain barrier?
Assistant: No, it is not permeable through the blood-brain barrier.
User: Is the molecule with the {SMILES__description} {SMILES#} {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, it is {p_np#not &NULL}{p_np__names__adjective}.
CC(=O)N1CCN(C(=O)Cc2ccc(C(F)(F)F)cc2)[C@@H](CN2CC[C@@H](O)C2)C1
CC(=O)N1CCN(C(=O)Cc2ccc(C(F)(F)F)cc2)[C@@H](CN2CC[C@@H](O)C2)C1
1-[(2S)-4-acetyl-2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]piperazin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone