User: Can you tell me if the molecule with the SMILES O=c1ncnc2[nH][nH]cc1-2 is permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: No, this molecule is not permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, this molecule is {p_np#not &NULL}{p_np__names__adjective}.
O=c1ncnc2[nH][nH]cc1-2
O=c1ncnc2[nH][nH]cc1-2
1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one