User: Is the molecule with the SMILES O=C1NC(=O)[C@@]2(CCN(C(=O)Cc3ccc(Cl)c(Cl)c3)[C@@H](CN3CCCC3)C2)N1 permeable through the blood-brain barrier?
Assistant: No, it is not permeable through the blood-brain barrier.
User: Is the molecule with the {SMILES__description} {SMILES#} {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, it is {p_np#not &NULL}{p_np__names__adjective}.
O=C1NC(=O)[C@@]2(CCN(C(=O)Cc3ccc(Cl)c(Cl)c3)[C@@H](CN3CCCC3)C2)N1
O=C1NC(=O)[C@@]2(CCN(C(=O)Cc3ccc(Cl)c(Cl)c3)[C@@H](CN3CCCC3)C2)N1
(5S,7R)-8-[2-(3,4-dichlorophenyl)acetyl]-7-(pyrrolidin-1-ylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione