Task: Please generate a molecule SMILES based on the description.
Description: A molecule that is not permeable through the membrane separating circulating blood and extracellular brain fluid.
Result: O=c1ncnc2[nH][nH]cc1-2
Task: Please {#give me|create|generate!} a {#molecule |!}{SMILES__description} based on the {#text |!}description{# below|!}.
Description: A molecule that is {p_np#not &NULL}{p_np__names__adjective}.
Result: {SMILES#}
O=c1ncnc2[nH][nH]cc1-2
O=c1ncnc2[nH][nH]cc1-2
1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one