User: Can you estimate if the molecule with the SMILES COC(=O)C1C2CC3c4[nH]c5cc(OC)ccc5c4CCN3CC2CC(OC)C1OC is permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: Yes, this molecule is permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, this molecule is {p_np#not &NULL}{p_np__names__adjective}.
COC(=O)C1C2CC3c4[nH]c5cc(OC)ccc5c4CCN3CC2CC(OC)C1OC
COC(=O)C1C2CC3c4[nH]c5cc(OC)ccc5c4CCN3CC2CC(OC)C1OC
methyl 6,17,18-trimethoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate