User: Can you estimate if the molecule with the SMILES COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-] is permeable through the membrane separating circulating blood and extracellular brain fluid?
Assistant: No, this molecule is not permeable through the membrane separating circulating blood and extracellular brain fluid.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is {p_np__names__adjective}?
Assistant: {p_np#No&Yes}, this molecule is {p_np#not &NULL}{p_np__names__adjective}.
COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]
COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate