User: I want to generate a SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the creation?
User: Yes, please. The molecule should not be active against the human immunodeficiency virus.
Assistant: Got it, this SMILES is not active against the human immunodeficiency virus: Cc1ccc(C=C2CN(C)CC3=C2OC(N)=C(C#N)C3c2ccc(C)cc2)cc1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
2-amino-6-methyl-4-(4-methylphenyl)-8-[(4-methylphenyl)methylidene]-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile