User: I want to come up with a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the creation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Ok, this SMILES is not active against HIV: CN1CC(=Cc2cccs2)C2=NC(=S)NC(c3cccs3)C2C1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
6-methyl-4-thiophen-2-yl-8-(thiophen-2-ylmethylidene)-4,4a,5,7-tetrahydro-3H-pyrido[4,3-d]pyrimidine-2-thione