User: I want to create a SMILES.
Assistant: This sounds very interesting. Should I consider any specific points for the generation?
User: Yes, please. The molecule should not be active against the human immunodeficiency virus.
Assistant: Got it, this SMILES is not active against the human immunodeficiency virus: CC(=O)ON1C(c2ccc([N+](=O)[O-])cc2)OCC2OC(n3cc(C)c(=O)[nH]c3=O)CC21
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
[6-(5-methyl-2,4-dioxopyrimidin-1-yl)-2-(4-nitrophenyl)-2,4,4a,6,7,7a-hexahydrofuro[3,2-d][1,3]oxazin-1-yl] acetate