User: I want to generate a molecule SMILES.
Assistant: This sounds very interesting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be active against the human immunodeficiency virus.
Assistant: Ok, this SMILES is not active against the human immunodeficiency virus: COC(=O)C1=C(C(=O)OC)C2OC1C1C2C2(C)C(C)=C(C)C1(C)S2=O
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
dimethyl 3,4,5,6-tetramethyl-12-oxo-11-oxa-12λ4-thiatetracyclo[6.2.1.13,6.02,7]dodeca-4,9-diene-9,10-dicarboxylate