User: I want to come up with a molecule SMILES.
Assistant: This sounds very interesting. Should I consider any specific points for the generation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Got it, here you go, this SMILES is not active against HIV: CCC1NC(=O)C(C(O)C(C)C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(CCCCNC(=O)COc2ccc(Sc3c(O)cc(-c4ccccc4)oc3=O)c(C(C)(C)C)c2)NC(=O)C(CC(C)C)N(C)C(=O)C(C(C)C)NC(=O)C(CC(C)C)N(C)C(=O)C(CO)N(C)C1=O
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
2-[3-tert-butyl-4-(4-hydroxy-2-oxo-6-phenylpyran-3-yl)sulfanylphenoxy]-N-[4-[20-ethyl-23-(hydroxymethyl)-17-(1-hydroxy-2-methylpropyl)-5,7,10,13,16,22,25,31-octamethyl-8,11,26,32-tetrakis(2-methylpropyl)-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-14,29-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacont-2-yl]butyl]acetamide