User: I want to create a SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the creation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Got it, here you go, this SMILES is not active against HIV: CCOC(=O)c1c(N2CCCC2)nc(O)c(C(c2cccs2)c2c(O)nc(N3CCCC3)c(C(=O)OCC)c2O)c1O
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
ethyl5-[[5-ethoxycarbonyl-2,4-bis(oxidanyl)-6-pyrrolidin-1-yl-pyridin-3-yl]-thiophen-2-yl-methyl]-4,6-bis(oxidanyl)-2-pyrrolidin-1-yl-pyridine-3-carboxylate