User: I want to come up with a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the generation?
User: Yes, please. The molecule should not be active against the human immunodeficiency virus.
Assistant: Ok, this SMILES is not active against the human immunodeficiency virus: Clc1ccc(Nc2nnc(CNc3ccc(-c4nnc(Nc5ccc(Cl)cc5)s4)cc3)s2)cc1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
5-[[4-[5-(4-chloroanilino)-1,3,4-thiadiazol-2-yl]anilino]methyl]-N-(4-chlorophenyl)-1,3,4-thiadiazol-2-amine