User: I want to generate a SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Ok, this SMILES is not active against HIV: Cc1sc2c(c1C)c(=O)[nH]c1c(C#N)c(-c3ccc(Cl)cc3)cn12
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
11-(4-chlorophenyl)-4,5-dimethyl-7-oxo-3-thia-1,8-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,9,11-tetraene-10-carbonitrile