Task: Please predict if the molecule with the SMILES COc1ccc(S(=O)(=O)N2CCCC(C(=O)Nc3ccc(NC(=O)c4ccccn4)cc3)C2)cc1 is an allosteric inhibitor of the muscarinic acetylcholine receptor M1.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1ccc(S(=O)(=O)N2CCCC(C(=O)Nc3ccc(NC(=O)c4ccccn4)cc3)C2)cc1
COc1ccc(S(=O)(=O)N2CCCC(C(=O)Nc3ccc(NC(=O)c4ccccn4)cc3)C2)cc1
N-[4-[[1-(4-methoxyphenyl)sulfonylpiperidine-3-carbonyl]amino]phenyl]pyridine-2-carboxamide