There are more than 730 retail clinics throughout the U.S., and CVS Caremark, Wal-Mart Stores, Walgreen and Target all have plans to expand their number of clinics this year. Some have established new restrictions on in-store clinics, while others ban them altogether. Rhode Island has refused to let CVS Caremark open clinics in the state; Florida requires clinics to post a sign stating whether a physician is present and disclose staffers' credentials to patients; and California has mandated that retail clinics be owned by a physician. Meanwhile, some states, such as Texas and Wyoming, have reduced restrictions on the treatments that nurse practitioners can administer in the clinics, the Journal reports. In the debate over regulations, CVS Caremark has been working to demonstrate that its clinics adequately administer the appropriate treatments within the scope of services provided.