Takeda does not undertake to update any of the forward-looking statements contained in this press release or any other forward-looking statements it may make, except as required by law or stock exchange rule. Past performance is not an indicator of future results and the results or statements of Takeda in this press release may not be indicative of, and are not an estimate, forecast, guarantee or projection of Takeda�s future results. References 1 Banerji A, Hao J, Ming Y et al; Long-Term Efficacy and Safety of Lanadelumab: Final Results from the HELP Open-Label Extension Study. ACAAI 2020. 2 Riedl MA, Johnston DT, Lumry WR et al; Attack-Free Status During Extended Treatment with Lanadelumab for Hereditary Angioedema: HELP OLE Study Final Results. ACAAI 2020. 3 Banerji A, Riedl MA, Bernstein JA, et al; for the HELP Investigators.