WASHINGTON (dpa-AFX) - Informatica Corp. (INFA) Thursday slashed its second quarter guidance as persistent economic weaknesses in Europe and other parts of the globe led to a decline in demand for its data integration software. The news had a deleterious impact on Informatica shares which lost the most in a year. The stock is currently down $11.87 or 27.37% on the Nasdaq, in after-hours trade. Informatica now expects second quarter earnings of $0.16 to $0.17 per share, and adjusted earnings of $0.27 to $0.28 per share. In April, the company had forecast adjusted earnings of $0.35 to $0.37 per share. Analysts, based on consensus, currently expect earnings of $0.37 per share for the quarter. Analysts' estimates typically exclude special items. Informatica's adjusted earnings exclude about $0.11 per share in charges and tax benefits partly related to the amortization of acquired technology and intangible assets.