REGENXBIO's new gene therapy product candidate for the treatment of HAE utilizes NAV Vectors that are designed to deliver a gene encoding a therapeutic antibody that targets and binds to plasma kallikrein, a key protein left unregulated in patients with HAE. In addition, REGENXBIO and Neurimmune AG announced earlier today an exclusive license, development and commercialization agreement to discover and develop novel AAV gene therapies using NAV Vectors to deliver human antibodies against targets implicated in chronic neurodegenerative diseases, including tauopathies.