Our data indicates that Ionis Pharmaceuticals, Inc. is worth US$8.1b, and total annual CEO compensation is US$7.3m. (This figure is for the year to 2017). We think total compensation is more important but we note that the CEO salary is lower, at US$849k. We examined companies with market caps from US$4.0b to US$12b, and discovered that the median CEO compensation of that group was US$6.4m.