However, there's still a long way to go. Source: Exact Sciences via the American Cancer Society Facts & Figures, 2014. According to the American Cancer Society's latest data, more than 136,000 colorectal cancer cases are expected to be diagnosed per year, resulting in just over 50,000 deaths per year. It's the second leading cause of cancer death, trailing only lung and bronchus cancer. This is where Cologuard could come into play. It's convenient, relatively quick, and it could mark an easy first step in the screening process for millions of Americans. Furthermore, it's potentially beneficial for insurers to have you get this screening regularly done, as the cost of a Cologuard test will be far less than the long-term costs of cancer treatment. No. 4: Insurers are willing to work with Exact Sciences That brings us to the next major point: Insurers and the Centers for Medicare and Medicaid Services are starting to getting behind Cologuard as a smart screening option.