Check out the companies making headlines before the bell: International Flavors & Fragrances (IFF) – IFF will be combined with DuPont's (DD) nutrition business, under a deal struck over the weekend. DuPont shareholders will own 55.4% of the combined company, with IFF's shareholders owning the rest. DuPont will also receive a $7.3 billion cash payment. Amarin (AMRN) – Amarin received Food and Drug Administration (FDA) approval for its Vascepa drug, designed to reduce the incidence of heart attacks and strokes in high-risk patients. Amarin boosted its 2020 financial outlook following news of the approval. Horizon Therapeutics (HZNP) – Horizon said an FDA advisory committee voted to recommend approval of a new treatment for thyroid eye disease. The full FDA is expected to issue a decision on the drug by March, according to the company.