But when it comes to investing, Berkshire Hathaway CEO Warren Buffett says there are some businesses that are more likely to succeed than others. At the 2015 annual Berkshire Hathaway shareholder meeting, Buffett was asked which of his company's holdings were best poised to thrive during a period of high inflation. Buffett's response: The best business to own is one that doesn't require continuous reinvestment because it becomes more and more expensive as the value of a dollar drops.