Initiation of patient enrollment is expected by year-end. "With the approval of our CTA, we are excited to bring a first-in-class CRISPR-edited cell therapy for the treatment of type 1 diabetes to the clinic, an important milestone in enabling a whole new class of gene-edited stem cell-derived medicines," said Samarth Kulkarni, Ph.D., Chief Executive Officer of CRISPR Therapeutics. "The combination of ViaCyte's leading stem cell capabilities and CRISPR Therapeutics' pre-eminent gene-editing platform has the potential to meaningfully impact the lives of patients living with type 1 diabetes."