Roland E Schmieder: Received Speakers Bureau honoraria and is an advisory board member for Novartis. His University Hospital has also received grants from Novartis. Veselin Mitrovic: Employed by Kerckhoff-Klinik Forschungsgesellschaft mbH, has received grant/research support from Bayer and Novartis; honoraria from Bayer, Novartis and GlaxoSmithKline and is a consultant for Cardiorentis and a Board Member for Daichi Sankyo. Christian Hengstenberg: Received speakers bureau honoraria from AstraZeneca, Boehringer, Edwards, Novartis, and Symetis; Advisory Board member for Novartis.