EPITOPE is expected to enroll approximately 331 patients (50 in Part A and 281 in Part B) in approximately 20 to 40 centers across North America (Canada and the United States), Ireland, and Australia. The EPITOPE trial is a two-part trial: Part A is designed to assess the safety of Viaskin Peanut 100 µg and 250 µg to determine the highest safe dose, and Part B is designed to assess the safety and efficacy of the highest safe dose selected in Part A. In Part A, patients are randomized 1:2:2 to receive either placebo or Viaskin Peanut 100 mcg or 250 mcg for 3 months. A safety analysis will be performed after 3 months to determine the highest safe dose to be studied in Part B. If there are no safety concerns with either of the two doses, patients will continue on their respective treatment and remain on the same active dose or placebo they received in Part A. In Part B, patients will be randomized 2:1 to receive the selected dose of Viaskin Peanut or placebo.