Antidepressant drug safety issues are beginning to have a financial impact. Dow Jones reports: "GlaxoSmithKline PLC said its net income fell 6% in the fourth quarter, hurt by previously announced legal costs related to its anti-inflammatory product Relafen, and weaker sales of the antidepressant Paxil." "We had to absorb a number of hits," Chief Executive Jean-Pierre Garnier said, including generic competition to antidepressant Paxil and legal costs of £228 million in the latest quarter.