Elanco Animal Health Inc. plans to eliminate roughly 380 jobs worldwide, including 20% of its senior management, in a plan aimed at simplifying the company's structure and enabling future and planned investment. The Greenfield-based company – which intends to open a streamlined global headquarters in the Valley, an Indianapolis neighborhood just south of the Indianapolis Zoo – announced the restructuring in a press release Tuesday. Elanco Animal Health is an animal health company that produces medicines and vaccines for farm animals and pets. According to an SEC filing, Elanco's Board of Directors authorized the restructuring plan on Monday. The company said the change will help reduce organizational complexity, enable investment and increase productivity. Less than 100 of the impacted employees are in Indiana, a spokesperson for the company via email.