In 2014, Nita Ambani joined the Board of Directors at Reliance Industries. During her tenure, she made significant contributions to the company's governance and strategy. According to Reliance Industries' Annual Report 2022-2023, Nita received a sitting fee of Rs 6 lakh and a profit-based commission of Rs 2 crore. However, in August 2023, she stepped down from her position following the induction of her children, Isha, Akash, and Anant Ambani, to the board.