BIRMINGHAM, Ala.--(BUSINESS WIRE)-- Medical Properties Trust, Inc. (the "Company" or "MPT") (NYSE: MPW ) today announced that it reached a global settlement agreement with Steward Health Care System ("Steward"), its secured lenders ("the Lenders") and the Unsecured Creditors Committee ("UCC") that restores MPT's control over its real estate, severs its relationship with Steward and facilitates the immediate transition of operations to quality replacement operators at 15 hospitals around the country.