Britain's top share index rose on Wednesday as drugmakers gained on recommendations by bullish brokers, while software company Sage clawed back losses prompted by its reporting results. Britain's FTSE 100 was up 0.4% at 6,423.41 points at its close, with pharmaceutical stocks contributing the most to gains. GlaxoSmithKline, AstraZeneca and Shire combined to add more than 10 points to the index, with the sector lifted by a note from Morgan Stanley. AstraZeneca benefited from a double upgrade to "overweight" and GlaxoSmithKline saw its target price lifted. "AstraZeneca … has underperformed dramatically over the past year, but looks set to reap the rewards of heavy investment at an attractive valuation," Morgan Stanley said in the note. Sage led declines earlier in the trading session, yet recovered to trade up 0.1%.