Breneman and Weber are based in Irvine and will report to Tim Sandel, senior vice president and regional vice president for Wells' technology and life sciences division in Southern California. The bank has made strides in the region's technology sector, with a 30% increase in lending in the past year, according to Sandel. "Wells Fargo is investing billions of dollars in technology companies of all sizes and at all stages of development and is building the team to ensure the bank can continue to provide the best financial strategies for companies in light of the fact that access to capital is so critical to the business Wells Fargo serves," he said. Wells' commercial banking arm serves businesses with annual sales from $25 million to $750 million. The changes in that division come amid a shift in the bank's retail operations. L.A., OC Markets Earlier this month, the Business Journal reported Wells is combining its Los Angeles and Orange County markets as part of a cost-cutting program.