Longevity.Technology: mTORC1 inhibitors, or mechanistic target of rapamycin complex 1 inhibitors, represent a promising avenue in geroscience for promoting longevity and extending healthspan. This class of compounds targets the mTORC1 signaling pathway, which plays a central role in cellular growth, metabolism, and aging. By inhibiting mTORC1 activity, these compounds modulate cellular processes, ultimately exerting beneficial effects on aging-related pathways. Research suggests that mTOR is linked to myriad biological processes related to aging, including nutrient sensing, maintenance of proteostasis, autophagy, mitochondrial dysfunction, cellular senescence and decline in stem cell function [ 1 ]. mTORC1 inhibition can confer neuroprotection [ 2 ], and neurodegeneration is an area of high unmet need globally.