Three drug companies have paid two-thirds of the financial penalties paid out since November 2010: GlaxoSmithKline, Johnson & Johnson and Abbott Laboratories. In July, British drugmaker GlaxoSmithKline agreed to pay $3 billion in fines — the largest health care fraud settlement in U.S. history — for criminal and civil violations involving 10 drugs, including the diabetes pill Avandia. Eli Lilly & Co. and Pfizer Inc. have also paid penalties of more than $1 billion in recent years to settle allegations of improper marketing. The Pharmaceutical Research and Manufacturers of America's Vice President Matt Bennett responded to the report in a statement: "Our member companies devote significant resources to internal compliance programs and thorough investigations of any reported misconduct — activities that complement the government's enforcement efforts."