Bone graft substitutes are synthetic or natural materials that are used to promote bone healing and regeneration in the absence of autografts or allografts. These substitutes have become an increasingly popular option for bone grafting procedures, particularly in cases where harvesting bone from the patient's own body or a donor is not possible or desirable. The bone graft substitutes consist of bone morphogenetic proteins (BMP) and synthetic bone grafts. Moreover, synthetic substitutes dominate the industry, driving a surge in product launches. For instance, in June 2023, BONESUPPORT, an emerging company, introduced CERAMENT G, an antibiotic-eluting bone graft substitute. This innovative kit has not only enhanced surgical workflows but also improved ease of use and overall user efficiency.