In addition to news that sarilumab outperformed Humira in this trial, Sanofi and Regeneron have announced that the drug's US list price of $39,000 represents a savings of roughly 30% relative to Humira and etanercept (Amgen's Enbrel). The manufacturers are expected to adopt a similarly competitive pricing strategy in Europe in order to help increase sarilumab's market share. Such a move could put additional pressure on AbbVie, which has so far held dominance in the crowded anti-rheumatic drug market, to adjust the price of its blockbuster RA drug, Humira. Deemed cost-ineffective by the Institute for Clinical and Economic Review, Humira was responsible for 63% of AbbVie's 2016 revenue, though challenges from biosimilar adalimumab treatments are expected to erode its earnings in the coming years.