Turning to the ARISTADA product family. Net sales in the first quarter declined sequentially to $30.million reflecting the impact of larger-than-expected seasonal inventory fluctuations. To put this into context more than 3 week's worth of total inventory was drawn down from the distribution channel during the quarter. And inventory levels at the end of March were at the lowest we've seen since the end of 2017. In dollar terms the impact of this inventory drawdown was approximately $10 million during the quarter. Q1 ARISTADA net sales were also impacted by higher gross-to-net adjustments of 49%, an increase from 44% in the fourth quarter of 2018. This reflects a higher proportion of government sales in the quarter and other typical quarterly fluctuations. Looking ahead we expect gross-to-net adjustments to normalize to around 47% for the remainder of the year.