Pfizer earned $37.8 billion from sales of its COVID-19 vaccine Comirnaty last year, while Moderna made $18.4 billion from its vaccine Spikevax. Representatives for Alnylam, Moderna and Pfizer did not immediately respond to requests for comment on the new lawsuits. Moderna and Pfizer have denied the allegations in the earlier cases and argued that Alnylam's patents are invalid. Cambridge, Massachusetts-based Alnylam first sued Moderna and Pfizer last March. It filed another pair of complaints last July over an additional LNP patent, which were later consolidated with its earlier lawsuits. The lawsuits filed Friday include four new infringement claims against Pfizer and three against Moderna. The complaints are part of a wave of patent lawsuits filed by biotech companies over COVID-19 vaccines, including a case brought by Moderna against Pfizer last year in Massachusetts.