The broader Topix shed 3.7% to 1,510.87, its lowest since early September, in very active trade, with the volume hitting the heaviest since May 2018 at 4.13 billion shares, partly due to MSCI's quarterly index rebalance. In a sign of broad-based selling, all of the 33 sector sub-indexes on the Tokyo Stock Exchange were trading lower, with real estate, information and communication and fish and forestry being the worst three performers.