Cov-Compare's primary endpoint is to determine the immune response (Geometric Mean Titer – GMT of SARS-CoV-2-specific neutralizing antibodies) two weeks after completion of a two-dose immunization schedule administered in a four-week interval. Topline data are expected by September 2021 and submission to the UK's Medicines and Healthcare products Regulatory Agency for regulatory approval will follow, subject to the topline data. Juan Carlos Jaramillo, M.D., Chief Medical Officer of Valneva, commented, "We are extremely pleased to have achieved this important milestone in such a short period of time.